| January 20, 2021 | ||
| Fulham | 1 - 2 | Manchester United |
| Manchester City | 2 - 0 | Aston Villa |
| January 19, 2021 | ||
| Leicester City | 2 - 0 | Chelsea |
| West Ham United | 2 - 1 | West Bromwich Albion |
| January 18, 2021 | ||
| Arsenal | 3 - 0 | Newcastle United |
| January 17, 2021 | ||
| Manchester City | 4 - 0 | Crystal Palace |
| Liverpool | 0 - 0 | Manchester United |
| Sheffield United | 1 - 3 | Tottenham Hotspur |
| January 16, 2021 | ||
| Leicester City | 2 - 0 | Southampton |
| Fulham | 0 - 1 | Chelsea |
| West Ham United | 1 - 0 | Burnley |
| Leeds United | 0 - 1 | Brighton & Hov… |
| Wolverhampton Wanderers | 2 - 3 | West Bromwich Albion |
| January 14, 2021 | ||
| Arsenal | 0 - 0 | Crystal Palace |
| January 13, 2021 | ||
| Tottenham Hotspur | 1 - 1 | Fulham |
| Manchester City | 1 - 0 | Brighton & Hov… |
| January 12, 2021 | ||
| Wolverhampton Wanderers | 1 - 2 | Everton |
| Burnley | 0 - 1 | Manchester United |
| Sheffield United | 1 - 0 | Newcastle United |
| January 4, 2021 | ||
| Southampton | 1 - 0 | Liverpool |
