Monday, November 1, 2010
Guimaraes 2 - 0 Portimonense

Saturday, November 6, 2010
Paços de Ferreira 0 - 1 CD Nacional
Portimonense 2 - 2 Académica de Coimbra

Friday, November 5, 2010
Vitoria Setubal 3 - 3 Rio Ave

Sunday, November 7, 2010
Maritimo 1 - 1 Uniao de Leiria
Naval 1º Maio 1 - 1 Olhanense
Braga 2 - 3 Beira-Mar Braga
FC Porto 5 - 0 Benfica

Monday, November 8, 2010
Sporting Lisbon 2 - 3 Guimaraes

Friday, November 12, 2010
CD Nacional de Madeira 0 - 0 Maritimo

Saturday, November 13, 2010
Guimaraes 2 - 1 Braga D. Alfonso
Académica de Coimbra 1 - 2 Sporting Lisbon

Sunday, November 14, 2010
Olhanense 1 - 1 Beira-Mar
Rio Ave 3 - 1 Paços de Ferreira
Uniao de Leiria 1 - 0 Vitoria Setubal
Benfica 4 - 0 Naval 1º 
FC Porto 2 - 0 Portimonense

Friday, November 26, 2010
Vitoria Setubal 0 - 1 Académica de Coimbra

Saturday, November 27, 2010
Paços de Ferreira 1 - 0 Olhanense
Maritimo 2 - 0 Guimaraes
Sporting Lisbon 1 - 1 FC Porto

Sunday, November 28, 2010
Naval 1º Maio 0 - 1 Rio Ave José
Beira-Mar 1 - 3 Benfica
Braga 2 - 0 CD Nacional de Madeira

Monday, November 29, 2010
Portimonense 1 - 2 Uniao de Leiria