Friday, September 10, 2010
Guimaraes 2 - 1 Benfica

Saturday, September 11, 2010
Sporting Lisbon 0 - 0 Olhanense
FC Porto 3 - 2 Braga

Sunday, September 12, 2010
Maritimo 1 - 1 Paços de Ferreira
Portimonense 3 - 1 Rio Ave
Uniao de Leiria 2 - 1 CD Nacional de Madeira
Académica de Coimbra 3 - 0 Naval 1º Maio

Monday, September 13, 2010
Vitoria Setubal 0 - 0 Beira-Mar

Friday, September 17, 2010
Olhanense 2 - 0 Portimonense

Saturday, September 18, 2010
Beira-Mar 1 - 1 Maritimo
Guimaraes 1 - 0 Uniao de Leiria

Sunday, September 19, 2010
Rio Ave 2 - 2 Académica de Coimbra
Naval 1º Maio 0 - 0 Vitoria Setubal
Paços de Ferreira 2 - 2 Braga
Benfica 2 - 0 Sporting Lisbon

Monday, September 20, 2010
CD Nacional de Madeira 0 - 2 FC Porto

Friday, September 24, 2010
Braga 3 - 1 Naval 1º Maio

Saturday, September 25, 2010
Académica de Coimbra 3 - 1 Guimaraes
Maritimo 0 - 1 Benfica
FC Porto 2 - 0 Olhanense

Sunday, September 26, 2010
Portimonense 1 - 0 Beira-Mar
Uniao de Leiria 1 - 0 Rio Ave
Sporting Lisbon 1 - 1 CD Nacional de Madeira

Monday, September 27, 2010
Vitoria Setubal 1 - 0 Paços de Ferreira